Pep Guardiola to be a hard task master who will extract the best out of a side that has shone domestically but struggled against Europe's elite.
Mohamed Salah's early penalty in the return match on Thursday gave Liverpool a 1-0 victory in Italy but Klopp's side went out 3-1 on aggregate.
Manchester City kept alive their flickering hopes of a second Premier League title in three seasons, and increased West Bromwich Albion's relegation worries, with a 3-1 victory on Monday.
Manchester City moved to the brink of the Premier League title with an emphatic 4-0 win over Aston Villa on Wednesday as Edin Dzeko scored twice to leave them needing just a point from the final game of the season.
France and Spain will step up security ahead of the Champions League quarter-finals in Madrid and Paris on Tuesday and Wednesday nights, top officials said, as Islamic State threats cast a shadow over Europe's top club soccer tournament.
Pizzas are off the menu for Manchester City players as manager Pep Guardiola has imposed strict weight parameters on the squad breaching which will result in training bans, left back Gael Clichy has said.
Kevin de Bruyne struck twice to inspire Manchester City to a dominant 4-2 win at Crystal Palace on Saturday and move the champions level on points with Liverpool at the top of the Premier League table.
City must win at Spurs or Arsenal will be champions says Guardiola
Liverpool, beaten by Arsenal on Sunday, lead the table on 51 points from 23 games but City are up to 49 from 22 and Arsenal on 49 from 23.
Manchester City survived a scare to beat FC Copenhagen 3-1 in the first leg of their Champions League last-16 tie at the Parken Stadium on Tuesday, with Phil Foden scoring late to ensure a two-goal cushion ahead of the second leg.
Manchester City emerged from a trough of despair to beat Tottenham Hotspur 3-1 and move to within three points of the Premier League title at Wembley on Saturday.
Lewis Hamilton revealed he is a big Arsenal fan and 'has been waiting for' them to win the Premier League (PL) for his whole life.
The revamped Champions League will feature a tennis-style seeding system for the last-16 knockout phase, UEFA said.
Manchester City coach Pep Guardiola has denied a newspaper report that he tried to sign strikers Lionel Messi and Neymar from former club Barcelona in the close season.
All the action from La Liga and Serie A matches played on Monday
A brilliantly-worked goal by Ryan Christie and a Justin Kluivert penalty gave Bournemouth shock 2-0 Premier League win at home to 10-man Arsenal.
Chile showed more attacking flair but failed to execute the crucial final pass in a first half marred by injuries, with Peru's Luis Advincula subbed off in the 35th minute and Chilean midfielder Diego Valdes being replaced at half-time.
Eriksen sends message of support to Lockyer following cardiac arrest
Manchester City returned to the top of the Premier League by drawing 0-0 away to Manchester United in a disappointing local derby on Sunday.
The defenders signed contracts on Tuesday from Bayern Munich making United their third team together, and they could both feature in the squad's season opener on Friday against Fulham at Old Trafford.
Leicester City's attempts to sign Adrien Silva from Sporting Lisbon were dealt a blow on Wednesday, with FIFA saying it had rejected an FA petition to grant the midfielder an international transfer certificate.
Manchester City were sensationally knocked out of the FA Cup on Monday by third-tier Wigan Athletic who beat the 10-man Premier League leaders 1-0 in a stunning fifth round upset with a late goal by their talisman Will Grigg.
News of all that's transpired on and off the football field
Manchester City suffered a shock League Cup defeat at the hands of a reinvigorated Newcastle United, who reached the quarter-finals with a superb 2-0 away win on Wednesday that left the holders nursing the wounds of a bruising past eight days.
Greece beat England for the first time as striker Vangelis Pavlidis's double earned the visitors a richly-deserved 2-1 victory.
If newly rich Manchester City wanted to rile Manchester United during the close-season they certainly went about it the right way -- and not just by spending over 100 million pounds on new players. The arrivals of Carlos Tevez from United, Emmanuel Adebayor and Kolo Toure from Arsenal, Roque Santa Cruz from Blackburn and Gareth Barry from Aston Villa should certainly see City improve in the new Premier League season starting this weekend.
The following is the draw for the Champions League last 16 which was held in Nyon on Monday:
Liverpool lost the plot in Atalanta defeat, says Klopp
Round-up of matches from the opening weekend of the English Premier League 2024-25
Vaughan wants England management to take inspiration from Manchester City boss Pep Guardiola.
Liverpool reclaimed top spot in the Premier League with a 3-1 win over Burnley at Anfield on Saturday, but they were made to battle hard by a brave visiting side.
The former world number one said she hoped to motivate young girls into sports with the doll.
Celtic manager Brendan Rodgers has a goalkeeping dilemma to resolve before ManchesterCity turn up for their Group C Champions League match in Glasgow on Wednesday.
Arsenal exacted sweet revenge on West Ham United with a 6-0 away thrashing to stay right in the thick of the Premier League title race.
IMAGES from the Premier League matches played on Saturday
Arsenal's title hopes hit with 2-0 loss to Villa as Man City get boost
Real Madrid fought back from two goals down as Vinicius Jr grabbed a hat-trick in a thrilling 5-2 win over visitors Borussia Dortmund in the Champions League.
After a shaky start to England's European Championship campaign that had critics questioning his starting spot, Phil Foden insists his partnership with Jude Bellingham will only flourish.
While Sunday's clash was the last time Klopp and Guardiola will face off for Premier League points, as far as this year's title race is concerned it merely made things even more interesting with Arsenal ahead of Liverpool on goal difference and City one point back. All three have 10 games left.
Southgate had some concerning post-game comments, pointing to the players' conditioning after long and gruellingly seasons.